By Tim Graham
"I got a really good shot," Jackson said today at One Bills Drive. "I like my chances."
Jackson ventured to say he has "a 70 to 75 percent chance to play."
Bills coach Chan Gailey shared Jackson's confidence to play in a division game at Ralph Wilson Stadium.
"From the workout and the rehab this morning, it went extremely well," Gailey said. "It looks like he's going to practice Wednesday, and we'll see how he feels during the course of the week.
"I'm very optimistic."
If Jackson can go, then it would be a fortuitous development for the Bills. C.J. Spiller, Jackson's replacement and the NFL's leader in yards from scrimmage, went down with a shoulder injury Sunday against the Cleveland Browns.
Gailey said Spiller's injury isn't as bad as originally thought, and while Spiller hasn't been ruled out for the Patriots game, the coach said that was unlikely.
"I always wanted to be back to play against New England," Jackson said. "I always said that. But when you lose a guy like that, it adds to wanting to get back out there to help your team."
Jackson's return this Sunday would mean a speedy recovery from the knee injury he suffered on opening day against the New York Jets. The initial diagnosis was he could return in four weeks with an outside shot at three weeks. Sunday will be three weeks.
"If I think I can get out there and make a play to help my team and I'm not hindering them, then I'll be out there," Jackson said.
Jackson will receive rehab treatment on the knee all week and will try to practice Wednesday as much as he can. He was limited in practice last week.
He also said he would wear a custom-fitted knee brace when he comes back.
"I'm not sure what the trainers are saying," Bills quarterback Ryan Fitzpatrick said. "I'm sure that's between him and them and the coach. But it would be a big boost for us to get him out there.
"Having Fred out there, everybody here knows how much he means to our team in terms of the inspirational leader that he is, really the go-to guy that we look to in key situations. To have him back would be great."